正常组织和器官的放射损伤课件.pptxVIP

正常组织和器官的放射损伤;细胞和组织;放射效应;损伤反应的影响因素;BT定律;早期反应和晚期反应;功能性亚单位（FSUs）;20.1 Relationship between dose and probability of complications for different types of normal tissues. Curve A relates to a normal tissue in which the functional subunits are not arranged serially regardless of whether one or all subunits are exposed (i.e., regardless of fi eld size). It also applies to a normal tissue in which functional subunits are arranged serially if only one subunit is exposed (i.e., if the fi eld is small). Note that the curve is relatively shallow (i.e., the probability of a complication rises relatively slowly with dose). Curves B and C refer to a tissue with serially a rranged functional subunits; the complication curve gets steeper and moves to lower doses as the treatment fi eld size increases. For example, curves B and C, respectively, relate to 4 or 16 functional subunits exposed. (Note that the position of the curves in relation to the abscissae is arbitrary, resulting from two assumptions: that there is an e ffective D0 of 4 Gy for a survival curve for cells exposed to multiple doses of 2 Gy, and that 58 Gy in 2-Gy fractions sterilizes 10% of the functional subunits.) (Adapted from Withers HR, Taylor JMG, Maciejewski B. Treatment volume and tissue tolerance. Int J Radiat Oncol Biol Phys. 1988;14:751–759, with permission.);组织的放射病理学;Casarett分类;Michalowski分型;生长因子;再程放疗的问题;晚期损伤的评价;Late Effects of Normal Tissue (LENT) conference SOMA - subjective, objective, management criteria with analytic laboratory and imaging procedures.;常见组织的放射反应 QUANTEC;;造血系统;淋巴组织和免疫系统;口腔黏膜;食管;胃;肠;肺;肾;肝;膀胱上皮;神经系统;睾丸;卵巢;女性生殖器;血管和脉管系统;心脏;骨和软骨;谢谢！