华法林剂量调整的大注意事项.pptxVIP

1、不应任意开始或终止华法林治疗。较低的INR治疗区间（2.0-2.2）一般不会在一些小的操作（如：活检、拔牙等）过程中导致大量出血。 2、华法林的剂量应该根据一周的总量来调整，每日剂量应小幅度调整（即：+-10-15%）以保持药物浓度可控性。控制华法林1天的剂量约为一周总剂量的14%。 3、经上述调整4-7天后，再次检测INR以确保达到一个新的稳态，过早的监测反而会误导作用。4、仅75%的病人INR可保持在2-3的治疗区间内。常常有INR略低或略高（例如：1.8或3.3）的情况，不应因此大幅度调整剂量。 5、显著的INR变动（1.5或6.0）通常是由于漏服药物或服药过多、合并其他疾病、饮食改变和或新的药物（如抗生素）所致。 6、指导患者在告知医生之前，不可随意开始或停止服用任何处方药物、非处方药物或相关替代药物。如果已经发生上述情况，应该在4-5天后复查INR以评估潜在的药物相互作用。 7、通常增强华法林作用的药物的有：胺碘酮、甲硝唑、喹诺酮类、甲氧苄氨嘧啶/新诺明、奥美拉唑等；可减弱华法林作用的有：口服避孕药、抗甲状腺药物、含有维生素K的补品等。 8、鼓励患者坚持记录INR，以及任何药物、饮食或生活方式的改变情况。 9、调整华法林要遵循专科医生的治疗方案，可以有效的保证患者的INR尽可能保持在治疗目标范围内。关于INR水平和剂量调整可以通过电话或电子邮件沟通。INR过高时，患者也可以在医师指导下服用补充量的维生素K以预防出血。 INSERT THE TITLE OF YOUR PRESENTATION HERE FREE PPT TEMPLATES ALLPPT.com _ Free PowerPoint Templates, Diagrams and Charts Free PPT Templates - Widescreen(16:9) This PowerPoint Template has clean and neutral design that can be adapted to any content and meets various market segments. With this many slides you are able to make a complete PowerPoint Presentation that best suit your needs. This PowerPoint Template has clean and neutral design that can be adapted to any content and meets various market segments. With this many slides you are able to make a complete PowerPoint Presentation that best suit your needs. This PowerPoint Template has clean and neutral design that can be adapted to any content and meets various market segments. With this many slides you are able to make a complete PowerPoint Presentation that best suit your needs. Click to add title Click to add title Free PPT Templates - Widescreen(16:9) This PowerPoint Template has clean and neutral design that can be adapted to any content and meets various market segments. With this many slides you are able to make a complete PowerPoint Presentation that best suit your needs. This PowerPoint Template has clean and neutral design that can be adapted to any content and meets various market segments. With this many slides you are able to make a complete PowerPoint Presentation that best s