ICP-MS分析丽水地产灵芝中的重金属元素.PDFVIP

ICP-MS 分析丽水地产灵芝中的重金属元素  范蕾，刘敏，余乐，陈张金(丽水市食品药品与质量技术检验检测院，浙江 丽水 323000) 摘要：目的 采用电感耦合等离子体质谱法(ICP-MS)建立灵芝中砷(As)、汞(Hg)、铅(Pb)、镉(Cd)、铜(Cu) 5 种重金属元 素的测定方法。方法 采用微波消解仪进行消解，以 115 72 209 In 、 Ge、 Bi 为内标，采用ICP-MS 法测定丽水产地灵芝的菌 盖与菌柄中As 、Hg 、Pb 、Cd、Cu 的含量。结果 检测的5 种元素线性关系良好，相关系数r ≥0.999 1 。22 批样品中Cd 超出限度的有5 批， As 、Pb 超出限度的各有 1 批，Cu 超出限度的有2 批。Cu、Cd、Hg 在菌盖中的富集较多，As 、Pb 则在菌柄中富集较明显。结论 该方法灵敏、高效、准确，且分别测定了灵芝不同药用部位的重金属含量，对龙泉灵芝 栽培基地选择，人工种植过程中重金属含量控制等具有现实意义，可用于灵芝的安全性评价。 关键词：灵芝；金属元素；电感耦合等离子体质谱法 中图分类号：R284.1 文献标志码：B 文章编号：1007-7693(2019)07-0837-04 DOI: 10.13748/ki.issn1007-7693.2019.07.014 引用本文：范蕾, 刘敏, 余乐, 等. ICP-MS 分析丽水地产灵芝中的重金属元素[J]. 中国现代应用药学, 2019, 36(7): 837-840. Determination of Heavy Metals in Ganoderma from Lishui by ICP-MS FAN Lei, LIU Min, YU Le, CHEN Zhangjin(Lishui Institute of Food and Drug Quality and Technical Inspection, Lishui 323000, China) ABSTRACT: OBJECTIVE To detect 5 heavy metal elements including As, Hg, Pb, Cd and Cu in Ganoderma by inductively coupled plasma mass spectrometry(ICP-MS). METHODS The content of As, Hg, Pb, Cd and Cu in Ganoderma from Lishui were determined by ICP-MS using 115In, 72Ge and 209Bi as internal standard by microwave digestion. RESULTS The linearity of the 5 elements were good, and the correlation were ≥0.999 1. There were 5 batches of Cd exceeding the limit in the 22 batches of samples, one batch of As and Pb exceeding the limit, and 2 batches of Cu exceeding the limit. Cu, Cd and Hg accumulated more in the cap, while As and Pb accumulated more in the stalk. CONCLUSION The method is sensitive, efficient and accurate, and the content of heavy metals in different medicinal parts of Ganoderma are determined respectively. It has practical significance to select