赖氨匹林对人宫颈癌Hela细胞的抑制作用及其机制-药理学专业论文.docxVIP

with negative control group(0.46±0.69)%, there was not statistical difference of the early apoptotic rates in 1 mmol?L-1aspisol group(P0.05), but the early apoptotic rates of 5 and 10mmol?L-1group were higher than that of negative control group, there was statistical difference(P0.01). 5. The expression of P-ERK1/2 protein and COX-2 protein in Hela cells was down-regulated by aspisol (P0.01), but it did not affect total ERK1/2 expression (P0.05). Conclusion: Aspisol can inhibit cervical cancer Hela cells proliferation and induce apoptosis; The expression of ERK1/2 increases in Hela cells, and