双羰基还原酶催化的两步羰基还原反应-中国药科大学学报!.pdf

双羰基还原酶催化的两步羰基还原反应-中国药科大学学报!.pdf

学 报 408 JournalofChinaPharmaceuticalUniversity 2010,41(5):408-413 ·OriginalArticles· Twostepprocessfordiketoreductioncatalyzedbydiketoreductase WUXuri牞CHENChen牞LIUNan牞CHENYijun LaboratoryofChemicalBiology牞SchoolofLifeScience&Technology牞ChinaPharmaceuticalUniversity牞Nanjing210009牞China Abstract Diketoreductasecancatalyzeadoublereductionof牞diketoestertocorrespondingdihydroxypro βδ ductwithenantiomericexcess牗ee牘anddiastereomericexcess牗de牘bothgreatert

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