浅论肺部曲霉菌感染的诊治.pptVIP

CPA in a smoker with previous infection to Mycobacterium Kansasii, undernutrition and cirrhosis. Several episodes of severe hemoptysis treated by arterial embolization with long term treatment by Voriconazole. Axial (a,b), coronal (c,d) and sagittal (e,f) reformations in mediastinal (b,d,f) and lung windows (a,c,e). Typical bilateral fungus balls (stars) almost filling the cavities on the left side. Note small cavities within the left fungus ball and some irregular walls of the cavity on the right side. The fungus balls appear hypoattenuated compared to enhanced pleural thickening (yellow arrows) and alveolar consolidation (blue arrows) . Note hypertrophic systemic arteries (red arrows) * CPA in a smoker with previous infection to Mycobacterium Kansasii, undernutrition and cirrhosis. Several episodes of severe hemoptysis treated by arterial embolization with long term treatment by Voriconazole. Axial (a,b), coronal (c,d) and sagittal (e,f) reformations in mediastinal (b,d,f) and lung windows (a,c,e). Typical bilateral fungus balls (stars) almost filling the cavities on the left side. Note small cavities within the left fungus ball and some irregular walls of the cavity on the right side. The fungus balls appear hypoattenuated compared to enhanced pleural thickening (yellow arrows) and alveolar consolidation (blue arrows) . Note hypertrophic systemic arteries (red arrows) * Present by David Denning ECCMID 10th May 2015 in Barcelona 患者人群 Population 目的 Intention 干预手段 Intervention SoR QoE 文献 Reference 备注 Comment 伴有曲霉球的慢性肺曲霉病患者，不愿意或不能给予口服治疗，唑类药物多耐药以及不能手术治疗患者 CPA with aspergilloma, unwilling or unable to take oral therapy, multiazole resistance and inoperable 控制感染性疾病进展 Control of infection 两性霉素B腔内注射 Instillation of amphotericin B Deoxycholate into cavity C II 慢性肺曲霉病-局部空腔治疗 Local cavity therapy for CPA Giron, 1998; Kravitz, 2013 试验验性治疗 Present by David Denning ECCMID 10th May 2015 in Barcelona 患者人群 Population 目的 Intention 干预手段 Intervention SoR QoE 文献 Reference 备注 Commen