松针的化学成分和药理活性研究进展.PDF

• 278 • 现代药物与临床 Drugs Clinic 第 26 卷 第 4 期 2011 年 7 月 松针的化学成分和药理活性研究进展 1, 2 1* 1 张志琴 ，肖培云 ，刘光明 1. 大理学院 药学院，云南 大理 671000 2. 楚雄医药高等专科学校 药学系，云南 楚雄 675005 摘 要：松针是松科植物的针状叶，主要含挥发油、黄酮类、木脂素、色素、维生素、氨基酸和多种矿物质。松针的药用历 史悠久，研究证实其具有降血糖、调血脂、抗肿瘤、抗衰老、抗突变、抑菌、抗病毒和镇痛抗炎等药理作用。综述了近年来 国内外对松针的化学成分和药理活性研究的进展，为进一步研究、开发和利用松属植物资源提供参考。 关键词：松针；挥发油；黄酮类；抗肿瘤；抗衰老；抗菌 中图分类号：R282.71 文献标志码：A 文章编号：1674 - 5515(2011)04 - 0278 - 04 Advances in studies on chemical constituents and pharmacological action of pine needle 1,2 1 1 ZHANG Zhi-qin , XIAO Pei-yun , LIU Guang-ming 1. College of Pharmacy, Dali University, Dali 671000, China 2. Department of Pharmacy, Chuxiong Medical College, Chuxiong 675005, China Abstract: Pine needle is the leaves of Pinaceae plant. It mainly contains volatile oil, flavonoids, lignans, pigment, vitamin, amino acids, and many minerals. Pine needle’s application for medicinal purposes has a long history. Modern research suggests pine needle has many pharmacological effects such as fall in the blood sugar and blood fat, inhibititng tumor, anti-aging, antimutation, antibacterial, antiviral and analgesia. The recent research about chemical constituents and its pharmacological activities of pine needles both at domestic and abroad have been summarized in this paper, expect for providing a reference for the further study, exploitation, and utilizing of this resource. Key words: pine needles; volatile oil; flavonoids; antitumor; anti-aging; antibacterial 松针，别名猪鬃松毛、松毛、山松须，为松科 有丰富的 β-胡萝卜素、维生素Ｃ、维生素 E ，三者 植物的针状叶，植物来源主要有马尾松 Pinus 共同保护人体组织细胞免受氧化损害，延长细胞的 massoniana Lamb. 、红松P. koraiensis Sieb. et Zucc. 、 寿命，被称为抗氧化的“金三角”。松针资源分布广 黑松P. thunbergii Parl. 、油松P. tabuleaformis Carr. 、 泛，具有广阔的开发前景。笔者主要对松针的挥发 华山松 P. armandii Franch. 、云南松P.