分子免疫学-T细胞亚群.pptVIP

The molecular basis of Th2 differentiation The interplay of signals from the T cell receptor, the cytokine IL-4, and the TF GATA-3 and STAT6 Th2 differentiation is most dependent on IL-4 IL-4 STAT-6 Ag recognition by TCR GATA-3 Development of Th1 and Th2 subsets Th2 cell differentiation requires both GATA3 expression and STAT5 activation Nature Review Immunol, 2010 Differentiation of Th17 Subset Stimulated by zymosan, fungus, myobacteria Important cytokines for the Th17 differentiation Important trans