Bias and Confounding in Clinical Trials - Jaeger Medical Research 偏倚和混杂在临床试验-耶格医学研究.docVIP

Bias and Confounding in Clinical Trials January 12, 2009 Clinical trials aim to generate new knowledge on the effectiveness of healthcare interventions, whether they be therapeutic or diagnostic in nature. A rudimentary dictionary definition of bias is a one-sided inclination of the mind. In clinical trial design, bias (also known as systematic error) is any process or effect that produces results or conclusions that differ from the truth, i.e., may compromise the ability to draw valid conclusions from the clinical study. Therefore, many of the principles of clinical trial design are specifica