起搏器电极植入择部位起搏新进展.pptVIP

* Early work by Karpawich demonstrated that, in contrast to RV apical pacing, RV septal pacing (with participation of the conduction system) does not result in myofibrillar disarray of the LV free wall. These illustrations are from a canine heart. * The “Pacing Mode” trials (DANISH I., II, CTOPP and MOST) all required very long follow-up periods before demonstrating negative effects of RVA pacing. Even the DAVID trial, that looked at ICD patients with relatively poor LV function and no indication for pacing, still required a significant follow-up period (6 mo) to demonstrate the negative