乳房疾病的种类及治疗课件.ppt

* Advanced pagets disease * Nipple retraction * Inflammatory caricinoma * Angiosarcoma following breast radiation * THE ERALY DIAGNOSIS THE BETTER PROGNOSIS,AND ALSO A LONG TERM OF DISEAST FREE SURVIVAL * MEDIOLATERAL OBLIQUE AND CRANIOCAUDAL VIEW Benign tumor always with smooth margin Malignant tumor presentations are: 1:MICROCALCIFICATION 2:DISTORTION 3:SPICULATED MASS DENSITY * HIGH DENSITY MASS,LOCAL CANCERATION with spiculated mass, this is DCIS * Local amplification view,we can see Microcalcifications,more than 10 per centimeter square * BENIGN TUMOR * Spiculated mass with calcification and high density * Structure distortion * TARGETTING THERAPY NCCTG N9831+NSABP B-31: DFS Romond et al 2005 Years from randomisation 87% 85% 67% 75% HR=0.48; p0.0001 100 90 80 70 60 50 0 1 2 3 4 5 2-year median follow-up Pts (%) AC P AC PH n Events AC PH 1672 133 AC P 1679 261 * Chemotherapy followed by Trastuzumab ASCO 2006 :HERA trail 2Yr. DFS HR 0.64 P0.0001 OS HR 0.66 P=0.0115 100 80 60 40 20 0 Pts(%) Months from randomisation 12 36 1 year trastuzumab Observation 0 18 6 24 30 Events HR 95% CI p value 0.64 0.54, 0.76 0.0001 3-yearDFS 80.6 74.3 218 321 6.3% * Physiologic nipple discharge * Pathologic nipple discharge * Advanced Pagets disease * Retraction * Inflammatory carcinoma * Locally advanced carcinoma (Stage IIIB) * Angiosarcoma following breast radiation * Imaging Study Mammography Ultrasound Ductogram Magnetic Resonance (MR) Positron Emission Tomography (PET) * * * * * * * * * * * * 关爱生命热爱生活 * Thank you fou your attention! * * This slide shows that global breast cancer incidence, That is significantly north hemisphere incidence is higher than south hemisphere. whether white women incidence is higher than other colored women ?,we can say yes. 但最近十年中国仍无可信的流调学资料。估计增加48%左右 * MASTITIS * FIBERADENOMA * PAPALLOMA * anthracycline-based regimen and Taxel or docetaxel. Which is benefit ?for early stage b