2009年欧洲高血压指南-.doc

Reappraisal of European guidelines on hypertension management:a European Society of Hypertension Task Force document Giuseppe Mancia a,Ste′phane Laurent b,Enrico Agabiti-Rosei c, Ettore Ambrosioni d,Michel Burnier e,Mark J.Caul?eld f,Renata Cifkova g, Denis Cle′ment h,Antonio Coca i,Anna Dominiczak j,Serap Erdine k, Robert Fagard l,Csaba Farsang m,Guido Grassi n,Hermann Haller o, Anthony Heagerty p,Sverre E.Kjeldsen q,Wolfgang Kiowski r,Jean Michel Mallion s, Athanasios Manolis t,Krzysztof Narkiewicz u,Peter Nilsson v,Michael H.Olsen w, Karl Heinz Rahn x,Josep Redon y,Jose′Rodicio z,Luis Ruilope a1, Roland E.Schmieder a2,Harry A.J.Struijker-Boudier a3,Pieter A.van Zwieten a4, Margus Viigimaa a5and Alberto Zanchetti a6 Journal of Hypertension2009,27:2121–2158 Keywords:antihypertensive treatment,cardiovascular risk,guidelines, hypertension,organ damage Abbreviations:ACE,angiotensin-converting enzyme;BP,blood pressure; DBP,diastolic blood pressure;eGFR,estimated glomerular?ltration rate; ESC,European Society of Cardiology;ESH,European Society of Hypertension;ET,endothelin;IMT,carotid intima-media thickness;JNC, Joint National Committee;LVH,left ventricular hypertrophy;LVM,left ventricular mass;PDE-5,phosphodiesterase-5;PPAR-g,peroxisome proliferators-activated receptor-g;PWV,pulse wave velocity;SBP,systolic blood pressure;WHO,World Health Organization a Clinica Medica,University of Milano-Bicocca,Ospedale San Gerardo,Monza, Milan,Italy, b Pharmacology Department,Hopital Europeen Georges Pompidou, Paris,France, c Department of Medical an d Surgical Sciences,Clinic of Internal Medicine,University of Brescia,Brescia,d University of Bologna,Clinica Medica,Bologna,Italy, e Division o f Nephrology and Hypertension,Centre Hospitalier Universitaire,Vaudois,Lausanne,Switzerland,f William Harvey Research Institute,Barts and The London School of Medicine, Queen Mary University of London,London,UK,g Department of Preventive Cardiology,Institute of Clinical and Experimental Medicin