药物流行病学-实验流行病学.pptVIP

实验流行病学;学习目的;推荐参考文献 吴涛, 詹思延, 李立明. 流行病学实验研究发展历史. 中华流行病学杂志 2004; 25(7): 633-636. …; 1747年 苏格兰医师James Lind首次对比研究了用桔子、柠檬及其他干预治疗坏血病的疗效 ; ??????????????????????????????????? On May 20, 1747 he is ready to begin the first clinical nutrition experiment. ; group 1 drank one quart of cider a day group 2 gargled with sulfuric acid group 3 had two spoonfuls of vinegar, 3 times a day group 4 drank 1/2-pint seawater a day group 5 drank barley water group 6 ate two oranges and 1 lemon a day ;What happened? Only sailors who ate the oranges and lemon felt better. In fact, in onl