神经生物学：乙酰胆碱和其他神经递质.pptVIP

Recourses of extracellular adenosine and ATP Extracellular ATP: from vesicle excytosis; from broken cells. Extracellular adenosine transported from the inside of cells by nucleotide transporter. from degradation of ATP. ATP is present in high concentrations within the brain Cortex and hippocampus synaptic membranes exhibit higher activities of NTPDase1 and NTPDase2 ecto-5’nucleotidases and adenosine deaminase were found in most brain regions. 5’-核苷酸酶（转换），脱氨酶(腺苷导致失活) * 2. Purinoceptors Classification P1（adenosine）receptor P2（nucleotide） receptor P2X