导尿管长期留置患者尿培养病原菌分布及耐药性探讨.docxVIP

导尿管长期留置患者尿培养病原菌分布及耐药性探讨 刘忠　古丽加玛力·阿迪力 [摘要] 目的 探讨导尿管长期留置患者尿培养病原菌分布及耐药性。 方法 回顾性分析我院20XX年1～6月收集的导尿管长期留置患者共101例尿液培养资料，共含菌株181株，分析病原菌分布特点，同时检测耐药性。 结果 ①101例送检尿培养标本病原菌阳性率为98.02%（99/101），其中单一病原菌感染46例，包括细菌31例，真菌15例;混合病原菌感染53例，其中混合细菌感染30例，混合真菌感染3例，细菌伴真菌感染20例。②全部标本共分离病原菌株181株，其中革兰阴性杆菌105株，以大肠埃希菌为主，占比达33.333%（35/105）;革兰阳性球菌36株，以屎肠球菌为主，占比达38.889%（14/36）;真菌40株，以白色念球菌为主，占比達42.500%（17/40）。③101例送检尿培养标本分离病原菌中，革兰氏阴性菌、革兰氏阳性菌及真菌分别以大肠埃希菌、屎肠球菌为主、念珠菌为主;导尿管留置时间2年标本常用抗菌药物耐药率显著高于1年，1～2年标本（P0.05）;导尿管留置时间1～2年标本常用抗菌药物耐药率显著高于1年（P0.05）。 结论 导尿管长期留置患者尿培养病原菌种类繁多，多重细菌和多重耐药比例较高;故临床应重视对导尿管长期留置患者尿路感染防治工作。 [关键词] 导尿管;留置;尿培养;病原菌;耐药性 [中图分类号] R446.5 [文献标识码] B [文章编号] 1673-9701（2020）21-0150-03 Study on the distribution and drug resistance of pathogenic bacteria in urine culture of patients with long-term indwelling catheter LIU Zhong1 Gulijiamali·Adili2 1.Department of Laboratory Medicine， Jining Traditional Chinese Medicine Hospital in Shandong Province， Jining 272100， China; 2.Department of Laboratory Medicine， Xinjiang Uyger Autonomous Region Kashi Yingjisha Uighur Medical Hospital， Kashi 844500， China [Abstract] Objective To explore the distribution and drug resistance of urine culture pathogens in patients with long-term indwelling catheter. Methods 101 cases of urine culture materials collected from patients with long-term indwelling catheter in our hospital from January to June 20XX ， containing a total of 181 strains. The distribution characteristics of pathogenic bacteria was analyzed and the drug resistance was detected. Results ①The positive rate of pathogenic bacteria in 101 cases of urine culture specimens was 98.02%（99/101）， of which 46 cases were infected by a single pathogen， including 31 cases of bacteria and 15 cases of fungi; 53 cases were mixed pathogen infections， and 30 cases were mixed bacterial infections. There were 3 mixed fungal infections and 20 bacterial in combination with fungal infections. ②A total of 181 pathogenic strains were