女性慢性盆腔痛.pptVIP

间质性膀胱炎 粘膜皱襞 肾丝球状出血 4个象限中的3个 CPP可能由膀胱引起 CPP 和 IC 症状相似 需要考虑膀胱是潜在的来源，以及它是疼痛症候群中的一部分。 及早诊断和治疗膀胱源性的疼痛是必要的 它是常见又经常被误诊的 可能导致不必要的子宫切除 PUF 问卷可以对间质性膀胱炎进行简单的筛选 治疗简单，可在门诊完成 Symptoms of CPP and IC are similar Need to consider the bladder as the potential origin of pain, and it may be part of the pain syndrome. Improved diagnosis and earlier treatment of IC/Pelvic Pain with Bladder component are needed It is Prevalent and frequently misdiagnosed May result in unnecessary hysterectomy PUF questionnaire is a simple screening technique for IC Treatment is simple and is office based 木聚硫钠（爱泌罗）修复膀胱的保护层 木聚硫钠 PPS 炎症消除 Inflammation resolved Hanno PM. Urology. 1997;49(suppl 5A):93-99. IC一线用药  First –Line Choice of IC Treatment 爱泌罗是唯一FDA批准用于治疗间质性膀胱炎的口服药物，它能够缓解间质性膀胱炎引起的膀胱疼痛和不适感。 ELMIRON is the only FDA-approved oral therapy indicated for the relief of bladderpain or discomfort associated with IC ELMIRON [prescribing information]. Raritan, NJ: Ortho-McNeil Pharmaceutical, Inc. In Summary 木聚硫钠是治疗间质性膀胱炎的基础 应用4周有23% 的病患感觉症状缓解 3-6个月能达到理想的疗效2 (38% to 65%) 连续使用3年症状仍有改善3 (62%) 连续6个月用药未缓解的病人缺乏继续治疗的有意义或有风险的证据2 Pentosanpolysulfate may form a foundation for IC management 23% of patients experienced symptom reliefwithin 4 weeks1 Optimal clinical response may require 3 to 6months of continual therapy2 (38% to 65%) Progressive improvement shown for up to 3 years with continuous therapy3 (62%) In patients whose pain has not improved after 6 months of therapy, the clinical value and risks of continued treatment are unknown2 1. Data on file, ALZA Corporation. 2. ELMIRON [prescribing information]. Raritan, NJ: Ortho-McNeil Pharmaceutical, Inc; 2004. 3. Hanno PM. Urology. 1997;49(suppl 5A):93-99. 间质性膀胱炎的联合药物治疗 剂量 备注 爱泌罗?* Elmiron plus口服建议 diet 100 mg tid Treatment of pain related to IC 阿米替林 (Elavil?) 10 mg-25 mg qhs 抗抑郁药物，缓解慢性疾病引起的焦虑 治疗 羟嗪 (Atarax?) 10 mg-25 mg qhs or25 mg qam and qhs 治疗组胺介导反应和过敏反应 可缓解紧张和焦虑 可选联合药物 *ELMIRON is the only FDA-approved oral drug for the reli