丁苯肽软胶囊治疗血管性痴呆的临床观察.docVIP

丁苯肽软胶囊治疗血管性痴呆的临床观察 【摘耍】目的观察丁苯肽软胶囊治疗血管性痴呆(VaD)的疗效及 安全性。方法52例VaD患者被随机分为对照组及丁苯肽组，于治疗 前和治疗12周后分别对其进行MMSE和ADL评分并进行比较，同时评 价丁苯肽软胶囊的纱物不良反应。结果 两组治疗后的MMSE及ADL评 分较治疗前均有显著提高(Plt;0?01),与对照组相比，丁苯肽组治 疗后MMSE及ADL评分改善更为明显(Pl t ;0?01),且两组显效率比较 亦有显著性差异(Plt;0. 05) o结论丁苯肽软胶囊治疗VD疗效确切 且不良反应少，可作为临床用药选择。 【关键词】血管性痴呆;丁苯肽软胶囊;MMSE;ADL Abstract Objective To observe the curative effect of butylphthalide in treating vascular dementia and its safety? Methods 52 cases with vascular dementia were randomly divided into 2 groups: butylphthalide group and control group; MMSE and ADL scores were applied to patients in both groups b