基线睾酮水平与人类攻击行为的关系研究.docxVIP

基线睾酮水平与人类攻击行为的关系研究  　　摘要:睾酮是一种可以在男性的睾丸间质细胞、女性卵巢和胎盘的皮层细胞中合成并分泌的雄性激素,它可以调节个体的各种生理、形态和行为过程,对个体生存和繁殖至关重要.大量研究表明,睾酮与社会行为的关联存在双向性,睾酮可以调节社会行为,社会行为可以反馈并进一步影响睾酮水平.我们将关注点聚焦于睾酮与人类攻击行为之间的关联.早期研究发现,高睾酮水平个体表现出更高的攻击性;近期的研究根据挑战假设理论模型和生物社会地位模型得出,人体内的睾酮水平对竞争性相互作用具有高度反应性.此外,通过对大量研究的回顾与分析,我们总结出睾酮水平的变化可以通过增强杏仁核的反应性或减少前额叶皮质-杏仁核功能耦合来影响攻击行为.未来的研究者应考虑其他激素(如皮质醇)和人格特征调节睾酮和人类攻击行为之间关系的潜在作用,以及相关的生物学机制. 　　关键词:睾酮; 攻击行为; 挑战假设理论模型; 生物社会地位模型; 　　作者简介: *吴寅,E-mail:yinwu0407@gmail; 　　基金: 国家自然科学基金; 广东省教育厅教育科学规划青年项目(2018GXJK150); 深圳大学高水平大学二期建设(860-000002110601); 深圳大学研究生教育改革研究项目; 　　Abstract:Testosterone is an androgen synthesized and secreted by the Leydig cells of the testes in men, the thecal cells of the ovaries and placenta of women. It can mediate various physiological, morphological, and behavioral processes, and is vital to human survival and reproduction. A large number of studies have shown that there is a bidirectional relationship between testosterone and social behavior. Testosterone can regulate various social behaviors, which in turn feedback and affect the testosterone level. Early research showed that individuals with high testosterone level are more aggressive. According to the challenge hypothesis and the biosocial status model, recent studies have revealed that testosterone is highly responsive to competitive interactions. In addition, by reviewing these studies, we suggest that changes in testosterone can affect aggressive behavior by enhancing the reactivity of the amygdala or reducing PFC-amygdala functional coupling. Future research could consider the potential role of other hormones(such as cortisol) and personality traits in regulating the relationship between testosterone and human aggressive behavior, as well as related biological mechanisms. 　　Keyword:testosterone; aggression; challenge hypothesis; biosocial status model; 　　随着社会恶性暴力事件层出不穷,很多学科将关注点聚焦于人类攻击行为,但想要对攻击行为背后的复杂机制有更为深入的了解,就需要将实验心理学、社会心理学、神经科学、行为经济学和药理学的技术相结合从而推进社会神经内分泌学领域(Carreacute;amp;Olmste