止血障碍血栓形成.pptxVIP

Disorders of Hemostasis: ThrombosisHypercoagulabilityDefinition: Alteration in the hemostatic balance between blood fluidity and clot formation. This is due to genetic and acquired disorders which shift this balance toward excessive or inappropriate platelet aggregation and fibrin formation and predispose to thrombosis.Prethrombotic States10 - inherited abnormalities resulting from mutations affecting the function of coagulant proteins and natural inhibitors20 - acquired defects that either affect the endothelium, fluid flow or blood components. These defects are often superimposed on 10 def