第九章抗生素的生产.pptxVIP

第九章：抗生素的生产;抗生素的生产;; In 1928 Scottish bacteriologist Alexander Fleming reported the antibacterial action of cultures of a Penicillium species He observed that Penicillium notatum killed some of his Staph. aureus culture dishes Discovery by accident? Culture dishes contaminated when left out for two weeks while Fleming was on holiday, instead of being incubated ;;Discoverer of penicillin Born into a farming family in Scotland, moved to London at 13 Awarded Scholarship to study medicine ;Zone of Inhibition;Howard Florey;Ernst Chain;到目前为止，有8000多种抗生素，2/3是由放线菌（strepomyces）产