消化呼吸系统发生.pptxVIP

Chapter 23Development of digestive and respiratory systemⅠ.Primitive gut and its derivetivesForegutMidgutHindgut Oropharyngeal membrane Cloacal membrane Vitelline ductⅡ.Development of the digestive system1.Evolution of foregutEsophagus and stomachLiver and gallbladderPancreas (1) Development of the esophagusesophagus Epithelium simple to stratified recanalization incomplete recanalization esophageal stenosis esophageal atresia (2) Development of the stomach dorsal mesenteryMesentery ventral mesenteryDorsal border: greater curvature, fundusVentral border: lesser curvatureDorsal mesogastrium: omental bursa(3) Development of liver and gallbladder肝憩室Hepatic diverticulumCephalic limb: liverCaudal limb: gallbladder cystic ductSeptum transversumCommon bile duct原始横隔原始横隔原始横隔Congenital obstructive jaundice(4) Development of pancreasVentral pancreatic budDorsal pancreatic budVentral pancreatic ductDorsal pancreatic ductCommon pancreatic ductAccessory pancreatic ductAnnular pancreas2. Evolution of midgut and hindgut(development of intestine)(1)Midgut loopCephalic limbCaudal limbCaecal swelling (bud)CaecumAppendixSuperior mesenteric arteryPhysiological umbilical herniation rotate counter clockwiseurorectal septumCloaca Urogenital sinus Urinary bladder, urethraAnorectal canalRectum Upper part of anal canalCloacal membraneUrogenital membraneAnal membraneAnal pit(2) Evolution of hindgut (Separation of the cloaca)Separation of the cloacaPectinate line3.Congenital malformation of the intestine(1)Stenosis, atresia and duplication (2) Umbilical fistula and Meckel’s diverticulum vitelline fistula Vitelline cystVitelline ligament(3) Congenital umbilical hernia (4)Congenital Aganglionic Megacolon due to absence of parasympathetic ganglia in the bowel wall(5) Imperforate anusrectovaginal fistularectourethral fistula Rectourethral fistulaRectovesical fistula(6) Abnormal midgut rotationleft side colon nonrotation of the midgut reversed rotation of the midgut situs inversus vi