【医脉通】2017+EASL临床实践指南：急性（爆发性）肝功能衰竭的管理.pdfVIP

Clinical Practice Guidelines EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failureq European Association for the Study of the Liver ⇑ Summary syndrome of jaundice, coagulopathy and hepatic encephalopa- thy (HE). The presentation is very similar to that of a post- The term acute liver failure (ALF) is frequently applied as a gen- transplant ‘‘small for size syndrome” scenario. These syndromes eric expression to describe patients presenting with or develop- are not considered within the scope of ALF, but do feature in ing an acute episode of liver dysfunction. In the context of some ALF databases, such as the European Liver Transplant hepatological practice, however, ALF refers to a highly specific Registry (ELTR). Extensive liver trauma is also included in ALF and rare syndrome, characterised by an acute abnormality of liver databases, but is not a cause of ALF unless there is loss of both blood tests in an individual without underlying chronic liver dis- venous and arterial inflows. ease. The disease process is associated with development of a In the context of hepatological practice, ALF refers to a coagulopathy of liver aetiology, and clinically apparent altered highly specific and rare syndrome, characterised by an acute level of consciousness due to hepatic encephalopathy. Several abnormality of liver blood tests in an individual without under- important measures are imme