蛋白吸附再循环治疗11例重型肝炎临床观察.docVIP

蛋白吸附再循环治疗11例重型肝炎临床观察 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：蛋白吸附再循环治疗11例重型肝炎临床观察 1 1 资料与方法 2 13 观察项目 3 2 结果 4 3 讨论 4 文2：肺泡蛋白沉积症11例临床观察及治疗对比 5 1资料与方法 6 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 10 正文 蛋白吸附再循环治疗11例重型肝炎临床观察 文1：蛋白吸附再循环治疗11例重型肝炎临床观察 ［Abstract］ Objective To study the curative effect and mechanism of protein absorbent recirculating system(PA)in the treatment of patients with severe 21 patients with severe hepatitis were randomly divided into treatment group and control group included 11 cases who were treated for 26 times with PA totally，and with an average of 236 times per treatment time lasted for at least 6 hou，and interval time was for 2 or 3 the period，the symptoms and sig，blood routine test，serum biochemical test，serum ammonia，prothrombin and prothrombin time activity were group included 10 The survival rate was 7273% and 3000% in the treatment group and the control one the former，clinical symptoms remitted，hepatic encephalopathy and hepatorenal syndrome ameliorated after treatment with were significant differences in serum total bilirubin，ammonia，PT，PTA as well as other serum biochemical indexes before and after treatment with the treating coues were safe，no severe complicatio PA can markedly relieve symptoms，improve the unfavorable serum biochemical indexes，and increase the survival it may be regarded as one of the efficacious and safe mea for treating severe hepatitis. ［Key words］ protein absorbent recirculating system；severe hepatitis；liver failure;artificial liver 重型肝炎患者由于肝衰竭致体内毒性物质大量蓄积，从而引起肝性脑病、肝肾综合征、水电解质、酸碱平衡紊乱、出血等多种并发症，经内科综合治疗病死率仍高达80%以上［1］。但因肝脏具有强大的再生能力，在内科综合治疗的基础上如果有方法能改善患者体内环境，有效降低患者高胆红素、内毒素血症，为肝脏再生创造相对良好的体内环境，则患者能够度过危险期进而有机会获得康复。近年来开展的人工肝支持系统治疗就是基于这样的原理来设计的。国外有学者应用分子吸附再循环系统（MA）治疗各种重型肝炎、肝衰竭，能够较好清除患者体内毒素，提高患者生存率［2］。我院在添置国产蛋白吸附再循环治疗系统后，应用该方法治疗11例重型肝炎患者，现 总结 报告如下。 1 资料与方法 11 一般资料 治疗组11例为2004年10月～2006年10月住院重型肝炎患者，诊断符合2000年（西安）全国病毒性肝炎会议制定的诊断标准。男8例，女3例。年龄25～65岁，平均413岁。其中急性重型肝炎3例，亚急性重型肝炎1例，慢性重型肝炎7例。病原学：HAV感染1