化学工程与工艺3氯2羟丙基二甲基脱氢枞基氯化铵合成研究.pdfVIP

3-氯-2-羟丙基二甲基脱氢枞基 氯化铵的合成研究 3-氯-2-羟丙基二甲基脱氢枞基氯化铵合成研究 摘 要：由脱氢枞胺（DHA）和环氧氯丙烷合成 3-氯-2-羟丙基二甲基脱氢枞基 氯化铵（CHPDMDHA）。制备过程分三步进行：首先，以脱氢枞胺为主要原料 通过 Eschweiler-Clarke 反应制得 N,N-二甲基脱氢枞胺（DMDHA）；第二步是 DMDHA 与盐酸反应生成 N,N-二甲基脱氢枞胺盐酸盐；最后盐酸盐与环氧氯丙 烷反应，并用乙酸乙酯与乙醇的复合溶剂重结晶，得到产物 CHPDMDHA。用 FT-IR 和核磁共振表征了原料、中间体及产物的结构；离子色谱法（IC）测定了 产物的含量。 结果表明，用以上方法合成CHPDMDHA 时，操作简单，得到的 CHPDMDHA 产品与脱氢枞胺及N,N-二甲基脱氢枞胺相比具有较好的水溶性 关键字：脱氢枞胺； 环氧氯丙烷；3-氯-2-羟丙基二甲基脱氢枞基氯化铵 （CHPDMDHA）； N,N-二甲基脱氢枞胺（DMDHA） Study on the synthesis of 3-chloro-2-hydroxypropyl dimethyl dehydroabietyl ammonium chloride Abstract ：3-chloro-2-hydroxypropyl dimethyl dehydroabietyl ammonium chloride (CHPDMDHA) was synthesized from dehydroabietylamine (DHA) and epichlorodrin. The synthesis was done in three steps. First, DHA was transformed into N,N-dimethyl dehydroabietyl amine (DMDHA) through Eschweiler-Clarke Reaction. Second, the DMDHA was reacted with hydrochloric acid and translated into DMDHA hydrochloride. Third, the CHPDMDHA was obtained after the DMDHA hydrochloride had reacted with epichlorodrin and recrystallized using a solvent composed of ethyl acetate and ethanol. The structures of raw materials 、intermediates and final products were all characterized by FT-IR and NMR. The content o intermediates and final products was analyzed by IC. The experimental results showed that CHPDMDHA obtained by DMDHA and epichlorodrin had a good quality. The result of FT-IR and IC test showed the content of CHPDMDHA in the product was more than 85% Keywords ： Eschweiler-Clarke reaction ； 3-Chloro-2-hydroxypropyl dimethyl dehydroabietyl ammonium chloride (CHPDMDHA) ；hydrochloric acid 第一章 绪论1 1.1 课题概述1 1.1.1 松香型表面活性剂的简介1 1.1.2 国内外对松香系列表面活性剂的研究现状、研究进展1 1.2．CHPDMDHA 的制备方法3 1.2.1 N,N-二甲基脱氢枞胺的制备及其进展3 1.2.2 由中间产物制 CHPDMDHA 及其进展3 1.3 课题的研究目的和研究内容5 1.3.1 课题的研究目的和意义5