参考教程分析2016general introduction to enrinology,pituitary tumor.pptxVIP

General Introduction to Disorders of  Endocrinology and Metabolism; 【Objectives and Requirements】 To master the clinical features of the common endocrine diseases; diagnostic procedures and treatment principles. 2. To be familiar with the actions and regulations of the main hormones in endocrine system; the important regulation of hypothalamic-pituitary-target gland axis. 3. To understand the definition of endocrinology and its clinical importance. ;Main Contents;Definition of Endocrinology The endocrine system, along with the nervous system , has evolved to provide mechanisms for communication between cells and organs. Have been critical for the development and function of multicellular organisms. Regulate and thus permit grow and development, reproduction, metabolic homeostasis, and responses to changes in the environment such as provocative stimuli and stress. ; Organs of the endocrine System include : hypothalomus, pituitary, thyroid, parathyroid, adrenal, pancreas, gonads, as well as others, such as the Heart(atrial natriuretic factor), Liver(insulin-like growth factor, Kidney(renin, erythropoietin, VitD), and Gastro-intestinal tract, etc.;Interchanging site for nervous impulse and endocrine activity;from nucleus supraopticus;Relationship Among Hypothalamic, Pituitary, Target Gland Secretion Hypothalamus CRH (Cortiocotropin-releasing hormone) Stimulate ACTH secretion PIF (Dopamine) Inhibits prolactin secretion GnRH (Gonadotropin-releasing hormone) Stimulate LH and FSH secretion GHRH (Growth- hormone releasing hormone) Stimulate GH secretion GHIH (Somatostatin) Inhibits GH secretion TRH ( Thyrotropin-releasing hormone) Stimulates TSH and prolactin secretion Anterior pituitary ACTH ( Adrenocorticotropic hormone) Stimulate synthesis and secretion of