分次稀释替代注射在儿童低剂量心脏CT血管成像中.docVIP

分次稀释替代注射在儿童低剂量心脏CT血管成像中 文档信息 ： 文档作为关于“医学心理学”中“医学影像”的参考范文，为解决如何写好实用应用文、正确编写文案格式、内容素材摘取等相关工作提供支持。正文11330字，doc格式，可编辑。质优实惠，欢迎下载！ 正文 分次稀释替代注射在儿童低剂量心脏CT血管成像中 文1：分次稀释替代注射在儿童低剂量心脏CT血管成像中 the role of split-bolus injection of diluted contrast medium in pediatric low-dose cardiac ct angiography li he-hong， wu ru-wei. dept radiology of guangzhou women children medical care center， guangdong， china， 510120 [abstract] objective to discuss the role of a split-bolus contrast medium injection protocol in the cardiac chambe and coronary arteries at pediatric cardiac computed tomographic(ct)angiography. methods patients who had undergone clinically indicated contrast enhanced 64-section multi-detector row ct angiography of the heart at guangzhou children’s hospital between may 2008 and november this period， 126 patients had undergone 64-section cardiac ct angiography. the human research committee approved this study and waived informed coent: 35 were injected by using a biphasic protocol with a dual-syringe injector; and 91 were injected by using a split-bolus protocol with a dual-syringe injector and an initial bolus of contrast medium with /kg rate followed by /kg speed of a 70%:30% saline to contrast medium mixture and a 4-25ml saline chaser. two radiologists rated the visualization of right and left heart structures and the degree of streak artifacts. data were analyzed with one-way analysis by for windows. results data for 56 girls and 70 boys(mean age， yea)wereincluded. mean contrast medium attenuation in the right heart was significantly(p [key words] split-bolus; cardiac; ct; pediatrics 64层ct已广泛应用于心脏血管及冠脉成像检查，由于64层ct扫描速度快于对比剂密度峰值在血液内的推进和循环速度，所以只需保证扫描点追随对比剂峰值区域，而无须注射大量的对比剂以保持长范围的峰值长度[1]，因此成人冠脉ct成像广泛使用经典的造影剂加生理盐水的双筒注射方案，能有效减少造影剂用量，减轻上腔静脉及右心的条纹状伪影，达到高质量的心脏大血管及冠脉显影效果[2]。然而此方案在应用于儿童先天性心脏病的心脏ct血管成像中，右心仍存在严重伪影[3]，严重干扰右心结构观察，影响相关复杂性先天性心脏病的临床诊断。本文探讨一种分次稀释注射方案在儿童心脏ct血管造影中的应用价值，以期避免和降低腔静脉和右心的严重造影剂高浓度伪影，也进一步减小造影剂的在小儿心脏扫描过程中的使用量。 材料与方法 经医院伦理委员会审核同意，126例先天性心脏病患儿在术前进行了ccta扫描，全部病例来源于广州市儿童医