HBeAg阴性慢性乙型肝炎中医证型分布及与HBVDNA肝纤四项关系的研究.doc

HBeAg阴性慢性乙型肝炎中医证型分布及与HBVDNA肝纤四项关系的研究 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：HBeAg阴性慢性乙型肝炎中医证型分布及与HBVDNA肝纤四项关系的研究 1 1 对象与方法 3 2 结果 4 3 讨论 5 文2：HBeAg阴性慢性乙型肝炎的诊断与治疗 8 1 诊断 8 2 治疗 9 3 预后 11 参考文摘引言： 12 原创性声明（模板） 13 文章致谢（模板） 13 正文 HBeAg阴性慢性乙型肝炎中医证型分布及与HBVDNA肝纤四项关系的研究 文1：HBeAg阴性慢性乙型肝炎中医证型分布及与HBVDNA肝纤四项关系的研究 Abstract：Objective To research the distribution characteristic of TCM syndrome types and their relatiohip with laboratorial tests in patients with HBe antigen-negative chronic hepatitis B. Method Clinical epidemiological retrospective investigation was adopted. 329 cases of Guangdong Provincial Hospital of TCM frome January 2008 to May 2009 were involved， and their hepatic function， HBVDNA and hepatic fibrosis marke were tested. Result The proportio of TCM type of syndromes in 329 patients included the survey were：liver depression and iufficiency of the spleen (type A) ＞ dampness-heat accumulation (type B) ＞ liver-kidney yin deficiency (type C) ＞ obstruction of colletarals by blood stasis (type D) ＞ iufficiency of both the spleen and the kidney (type E). The serum levels of ALT and AST in type B were significantly more higher than the other syndromes (P＜). When the range of replication of HBVDNA below 104 copies/mL， the frequency of type B was remarkably less than that of the other types， which was opposite when the range of replication of HBVDNA between 104 copies/mL and 107 copies/mL (P＜). The percentage of type B with abnormal PCⅢ was higher than type A and type C， while the percentage of type C with abnormal LN or HA and the percentage of type D with abnormal HA were higher than type A and type B (P＜). There was no difference between the rate of abnormal CⅣ in type A and that in type B (P＞). Conclusion The distribution of TCM types of syndrome of the patients with HBeAg-negative chronic hepatitis B has its characteristic. There are some relatiohips between TCM types of syndrome and the levels of traaminases， HBVDNA， the abnorma