浙江大学《遗传学》课件-chapter12 Chromosome.pptVIP

Duplication Gain of a extract chromosome segment in the same chromosome Resulted from unequal cross-over or segregation of balanced abnormality 18q23 18 Dup (18) 46,XY,dup (18)(q23) 46, XY, dup(18)(pter -cen-q23::q23::qter) 46,X, dup(X)(q13q26) 46, X, dup(X)(pter-q26::q13q26::q26-qter) Insertion Gain of a extract chromosome segment from the different chromosome Resulted from segregation of balanced abnormality Father 46, XY, t(3;11)(q27;q13), ins(11;3)(q13;p26p13) Son 46, XY, der(11) ins(11;3)(q13;p26p13) Isochromosomes One arm is deleted and the other duplicated One arm is mono