变应原免疫治疗进展 20160327.pptxVIP

变应原免疫治疗研究进展The progress of Allergen Immunotherapy research 重庆新桥医院 程晓明 Mar 27th 2016 重庆 1 . 变应性疾病-如影相随 Gupta R, et al. BMJ. 2003 Nov 15x;327(7424):1142-3 Ninan TK, et al. BMJ. 1992 Apr 4;304(6831):873-5 2 . 历史变迁 Larché M, et al. Nat Rev Immunol. 2006;6(10):761-71 Von Pirquet 3 . 是Specific Immunotherapy (SIT) 还是Allergen Immunotherapy (AIT)? Calderón MA, et al. Allergy. 2013;68(7):825-8 4 . AIT的机制是什么？ Akdis CA, et al. World Allergy Organ J. 2015;8(17): 1-12. Mechanisms of allergen-specific immunotherapy and immune tolerance to allergens. 5 . AIT可能的推手-Treg和Breg Akdis CA, et al. World Allergy Or