Alflutinib-Furmonertinib-DataSheet-生命科学试剂-MedChemExpress.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE Alflutinib Cat. No.: HY-112870 CAS No.: 1869057-83-9 Synonyms: Furmonertinib; AST2818 分⼦式: C₂₈H₃₁F₃N₈O₂ 分⼦量: 568.59 作⽤靶点: EGFR 作⽤通路: JAK/STAT Signaling; Protein Tyrosine Kinase/RTK 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 Alflutinib is a potent inhibitor of EGFR. Alflutinib inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Alflutinib has the potential for the research of cancer diseases, especially non- small cell lung cancer (NSCLC) [1]. IC50 Target EGFR 体外研究 AST2818 is designed to inhibit EGFR active mutations as well as the T790M acquired resistant mutation [1]. 客户使⽤本产品发表的科研⽂献 • Patent. US20220177473A1. See more customer validations on www.MedChemE REFERENCES [1]. Y. Shi, et al. P2.03-028 Third Generation EGFR Inhibitor AST2818 (Alflutinib) in NSCLC Patients with EGFR T790M Mutation: A phase1/2 Multi-Center Clinical Trial. McePdfHeigh