环素类及氯霉素类.pptxVIP

第43章 四环素类及氯霉素类 Chapter 43  Tetracyclines and Chloramphenicols;四环素类（tetracyclines）和氯霉素类（chloramphenicols）抗生素的抗菌谱广，包括革兰阴性菌和革兰阳性菌、立克次体、衣原体、支原体、螺旋体，还具抗阿米巴原虫的作用，故常称之为广谱抗生素（“broad-spectrum” antibiotics）。 ;The tetracyclines are active against a wide range of aerobic and anaerobic gram-positive and gram-negative bacteria. They also are effective against some microorganisms that are resistant to cell-wall-active antimicrobial agents, such as Rickettsia, Coxiella burnetii, Mycoplasms pneumoniae, Chlamydia spp., Legionella spp., Ureaplasma, some atypical mycobacteria, and Plasmodium spp. They are no