高乳酸与休克课件.pptVIP

乳酸清除率＝（初始乳酸值－复测血乳酸值）/ 初始乳酸值x100% 高乳酸时间( lactime)乳酸 2mmol/L所持续时间 乳酸清除率 229个重症脓毒症和脓毒症休克病人，根据24-48h内的乳酸清除率将患者分为两组： 院内30天的死亡率对比结果如图： 结果说明:乳酸清除率低与死亡率高相关，乳酸清除率可以指导脓毒症休克患者的后期治疗。 Chertoff, J., et al. (2016). Prognostic utility of plasma lactate measured between 24 and 48 h after initiation of early goal-directed therapy in the management of sepsis, severe sepsis, and septic shock. J Intensive Care 4: 13. 同样说明:乳酸清除率低的患者死亡率高，并且乳酸清除率还可以指导将患者进行危险分层。 Bhat, S. R., et al. (2015). Lactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe Sepsis. West J Emer