第七章抗肿瘤药课件.pptxVIP

28 四月 2023;Classification by mechanism;13.1 Biological alkylating agents;;;Mechlorethamine hydrochloride;Different R：脂肪氮芥、芳香氮芥;Alkylation;It is usually used as injection drug of aqueous solution, which pH value maintained at 3.0 ~ 5.0.;Nitromin: Reduced the possibility of formation of ethylene imine for the reduced electronic cloud on nitrogen. Nitromin is less toxicity, but also the reduced anti-tumor activity.;;Cyclophosphamide;Physicochemical properties of cyclophosphamide;Cyclophosphamide has a broad spectrum of anti-tumor, clinical for treatment of malignant lymphoma, acute lymphocytic le