剥皮性过敏药物过敏反应.docxVIP

剥皮性过敏药物过敏反应 Chapter 1: IntroductionIntroduction to drug allergies and adverse reactions:Drug allergies are immune responses triggered by specific medications. These reactions can range from mild skin irritations to severe, life-threatening complications. Adverse drug reactions (ADR) are a significant public health concern, affecting a substantial proportion of the population. Among various drug classes, skin-removing medications, such as depilatories and exfoliants, are known to cause a significant number of allergic reactions. This study aims to explore the mechanisms, symptoms, and management of skin-removing drug allergies.Chapter 2: Mechanisms of Skin-Removing Drug Allergies2.1 Overview of the immune response:The immune system plays a crucial role in allergic reactions. In the case of drug allergies, certain medications act as allergens, triggering an immune response. This response involves the recognition of the drug as a foreign substance and the subsequent activation of immune cells, including T cells and B cells.2.2 Mechanisms of skin-removing drug allergies:Skin-removing drugs contain active ingredients that break down the proteins in the hair and skin, facilitating their removal. However, these active ingredients can also elicit an allergic response. The most common mechanism of skin-removing drug allergies is haptenization, in which the drug acts as a hapten, binding to a larger carrier protein. This hapten-protein complex is recognized by the immune system, leading to an immune response and subsequent allergic reaction.Chapter 3: Symptoms and Diagnosis3.1 Symptoms of skin-removing drug allergies:Allergic reactions to skin-removing medications can manifest as various symptoms, ranging from mild to severe. Common symptoms include itching, rash, redness, swelling, and pain at the application site. In more severe cases, systemic symptoms such as difficulty breathing, dizziness, and anaphylaxis may occur.3.2 Diagnosis of skin-removing drug alle