肾上腺髓质素对血管钙化的抑制作用课件.pptxVIP

Department of Physiology and Pathophysiology, Peking University Health Science Center Key Laboratory of the Ministry of Education on Molecular Cardiology Yong-Fen Qi Adrenomedullin inhibits vascular calcification 1 Vascular calcification is believed to be an important risk factor of cardiovascular diseases Media Intima Aging 2 Vasoactive peptides: Adrenomedullin ? 3 n Adrenomedullin (ADM) is a peptide capable of inducing a potent and long lasting hypotensive effect n ADM is mainly synthesized and secreted from vascular endothelial and smooth muscle cells (VSMC) n ADM has been shown to ha