慢性酒精中毒性脑病课件.pptVIP

酒精中毒性小脑变性 临床表现为 躯干及下肢的共济失调、眼球震颤、言语缓慢、行走不稳，部分患者合并周围神经损害。临床需要与遗传性共济失调、亚急性小脑变性鉴别。 影像特征： 小脑萎缩：主要是小脑蚓部上端萎缩明显 脑池扩大：环池、小脑上池、枕大池等 1.Fitzpatrick LE, Jackson M, Crowe SF. The relationship between alcoholic cerebellar degeneration and cognitive and emotional functioning[J]. Neuroscience and Biobehavioral Reviews , 2008, 32(2008): 466-485. ?2.Yokota O, Kuniaki T, Seishi T, et al. Frequency and clinicopathological characteristics of alcoholic cerebellar degeneration in Japan: a cross-sectional study of 1,509 postmortems[J]. Acta Neuropathol , 2006, 11