瘦素受体在特发性血小板减少性紫癜患者树突细胞的表达的开题报告.docxVIP

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瘦素受体在特发性血小板减少性紫癜患者树突细胞的表达的开题报告.docx

瘦素受体在特发性血小板减少性紫癜患者树突细胞的表达的开题报告

Introduction/Introduction:

Idiopathicthrombocytopenicpurpura(ITP)isanautoimmunediseasecharacterizedbythedecreasedplateletcountduetoplateletdestructioninthereticuloendothelialsystemorsuppressionofplateletproductioninthebonemarrow.Thrombopoietin(TPO)isakeyhormoneintheregulationofthrombopoiesis,theprocessofplateletproduction.TPOactsthroughitsreceptor,theTPOreceptor(c-MplorCD110),whichisexpressedonmegakaryocytesandtheirprecursors.TPOisproducedmostlybyliver,butalsobyotherorgans,su

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