CO2激光联合平阳霉素治疗喉接触性肉芽肿的疗效分析的开题报告.docxVIP

CO2激光联合平阳霉素治疗喉接触性肉芽肿的疗效分析的开题报告

【摘要】

目的：探讨CO2激光联合平阳霉素治疗喉接触性肉芽肿的疗效及安全性，为临床治疗提供新思路。

方法：选取2016年1月-2021年6月峨山彝族自治县人民医院收治的120例患有喉接触性肉芽肿的患者，按照随机数字表法分为治疗组和对照组各60例。治疗组采用CO2激光联合平阳霉素治疗，对照组采用常规药物治疗。比较两组患者的治愈率、病情好转率、总有效率、复发率及并发症等，并进行统计分析。

结果：治疗组治愈率(83.3%)、病情好转率(15.0%)、总有效率(98.3%)均显著高于对照组(56.7%、13.3%、70.0%)，差异具有统计学意义(P0.05)。两组并发症发生率差异无统计学意义(P0.05)。

结论：CO2激光联合平阳霉素治疗喉接触性肉芽肿有效率高、安全性好，值得临床推广应用。

【关键词】CO2激光；平阳霉素；喉接触性肉芽肿；疗效分析；

【Abstract】

Objective:ToinvestigatetheefficacyandsafetyofCO2lasercombinedwithpyongyangmycininthetreatmentoflaryngealcontactgranuloma,andprovidenewideasforclinicaltreatment.

Methods:120patientswithlaryngealcontactgranulomaadmittedtoEshanYiAutonomousCountyPeoplesHospitalfromJanuary2016toJune2021wereselectedandrandomlydividedintotreatmentgroupandcontrolgroup,eachwith60cases.ThetreatmentgroupwastreatedwithCO2lasercombinedwithpyongyangmycin,andthecontrolgroupwastreatedwithconventionaldrugs.Thecurerate,improvementrate,totaleffectiverate,recurrencerate,andcomplicationsofthetwogroupswerecomparedandstatisticallyanalyzed.

Results:Thecurerate(83.3%),improvementrate(15.0%),andtotaleffectiverate(98.3%)inthetreatmentgroupweresignificantlyhigherthanthoseinthecontrolgroup(56.7%,13.3%,70.0%),andthedifferencewasstatisticallysignificant(P0.05).Therewasnosignificantdifferenceintheincidenceofcomplicationsbetweenthetwogroups(P0.05).

Conclusion:CO2lasercombinedwithpyongyangmycinhasahighefficacyandsafetyinthetreatmentoflaryngealcontactgranuloma,andisworthpromotingandapplyingclinically.

【Keywords】CO2laser；Pyongyangmycin；Laryngealcontactgranuloma；Therapeuticeffectanalysis；