维生素D相关文献Differences of Serum 25- (OH) D3 Level and Adverse Pregnancy Outcomes between Women with Gestational Diabetes and Healthy Pregnant Women.pdf

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IranJPublicHealth,Vol.50,No.1,Jan2021,pp.139-145OriginalArticle

DifferencesofSerum25-(OH)D3LevelandAdversePregnancy

OutcomesbetweenWomenwithGestationalDiabetesand

HealthyPregnantWomen

YingfengJIANG,JingZHANG,YuanLIU,TingHUANG,ZhengCAO,*XiangkuiSHI

DepartmentofPharmacy,XuzhouMaternityandChildHealthCareHospital,Xuzhou221009,P.R.China

*CorrespondingAuthor:Email:xm5fwi@163.com

(Received14May2020;accepted10Jul2020)

Abstract

Background:Thedifferenceinserum25-hydroxyvitaminD(25-(OH)D)levelbetweenthegestationaldia-

betesmellitus(GDM)andhealthypregnantwomenwasanalyzed,toprovidetheexperimentalevidenceforthe

vitaminsupplementinpregnantwomen,especiallythosewithGDM.

Methods:Pregnantwomen(n=50)whoreceivedprenatalcareintheObstetricalClinicofXuzhouMaternity

andChildHealthCareHospitalinsummerandwinterof2016wereenrolled.Theywereassignedtothesum-

merGDMgroup,winterGDMgroup,summercontrolgroupandwintercontrolgroup.Thelevelofserum25-

(OH)Dwasdeterminedusingimmunochromatography.

Results:Themeanlevelofserum25-(OH)D3inpregnantwomenoffourgroupswaslowerthannormallevel.

Comparedwithcontrolgroupincorrespondingseason,thewinterandsummerGDMgroupshadsignificantly

lowerlevelof25-(OH)D3thanthewinterandsummercontrolgroups(P0.05).ThewinterGDMgrouphad

significantlylowerlevelof25-(OH)D3thanthesummerGDMgroup(P0.05).Thewintercontrolgrouphad

significantlylowerlevelof25-(OH)D3

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