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Dataextractionform
Titleofreview
Reviewersname
StudyID–FirstAuthor,DateofPublication,Title,PlaceofPublication
Studydesign
ParallelgroupCrossoverOther(describe)
Isthestudyrandomised?
Isthestudydoubleblind?________________________
Participants
Diagnosis
Intervention1Intervention2Control
Diagnosticcriteriaofpatientsincluded
inthetrial(givedetailsofdiagnosis,
stageofdiseaseandclinicalpattern
suchassignificantbulbarsymptomsif
thisisavailable)
Age(mean,sd)
Sex(malen(%))
Numberofparticipantsenteredintrial
severity(mean,sd)orno.ofpatients
withsevere,moderate,mildcondition:
givedefinitionsinfootnote
Durationofcondition(units,mean,sd)
Intervention
Doesinterventionfulfilcriteriaforinclusion?
Intervention1Intervention2Control
Typeofintervention
Formulation
Timing/frequency
Duration
Setting
Lengthoffollow-up
Weretreatmentgroupscomparableatbaseline?
YesNoDon’tknow
Includestudy?
No(givereasonsforexclusion)
2of4
1
TheCochraneCollaboration’stoolforassessingriskofbias
DomainDescriptionReviewauthors’judgement
Sequencegeneration.Wastheallocationsequenceadequatelygenerated?
YES/NO/UNCLEAR
Allocationconcealme
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