racemic-Salsolinol-hydrochloride-生命科学试剂-MCE.pdf

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(±)-Salsolinolhydrochloride

Cat.No.:HY-113316A

CASNo.:79923-51-6

分⼦式:C₁₀H₁₄ClNO₂

分⼦量:215.68

作⽤靶点:EndogenousMetabolite;OpioidReceptor

作⽤通路:MetabolicEnzyme/Protease;GPCR/GProtein;Neuronal

Signaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(±)-Salsolinolhydrochloride是(±)-Salsolinol(HY-113316)的盐酸盐形式。(±)-Salsolinolhydrochloride是

⼀种Dopamine(HY-B0451)衍⽣的内源性代谢物。(±)-Salsolinolhydrochloride可激活μ-阿⽚受体(

MOR)，降低GABA能传递，增加多巴胺(dopamine，DA)神经元的兴奋性，从⽽加速后腹侧被盖区(pVTA)神

经元的持续放电。

IC50TargetHumanEndogenousMetabolite

REFERENCES

[1].XieG,etal.,Salsolinolmodulationofdopamineneurons.FrontBehavNeurosci.2013May24;7:52.

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