APL180-L-4F-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

APL180

Cat.No.:HY-P6365A

CASNo.:388566-97-0

Synonyms:L-4F

分⼦式:C₁₁₄H₁₅₆N₂₄O₂₈

分⼦量:2310.6

Sequence:Ac-Asp-Trp-Phe-Lys-Ala-Phe-Tyr-Asp-Lys-Val-Ala-Glu-Lys-Ph

e-Lys-Glu-Ala-Phe-NH2

SequenceShortening:Ac-DWFKAFYDKVAEKFKEAF-NH2

作⽤靶点:Apolipoprotein

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性APL180(L-4F)是⼀种载脂蛋⽩A-I模拟肽，可增强⾼密度脂蛋⽩(HDL)的抗炎活性。APL180可⽤于⼼⾎管疾

病的研究[1]。

REFERENCES

[1].WatsonCE,etal.,TreatmentofpatientswithcardiovasculardiseasewithL-4F,anapo-A1mimetic,didnotimproveselectbiomarkersof

HDLfunction.JLipidRes.2011Feb;52(2):361-73.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1