GSK-364735-potassium-S-GSK-364735-potassium-生命科学试剂-MCE.pdf

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GSK-364735potassium

Cat.No.:HY-16907A

CASNo.:912672-93-6

Synonyms:S/GSK-364735potassium

分⼦式:C₁₉H₁₈FKN₃O₄

分⼦量:410.46

作⽤靶点:HIV;HIVIntegrase

作⽤通路:Anti-infection;MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性GSK-364735potassium(S/GSK-364735potassium)是GSK-364735(HY-16907)的钾盐形式。GSK-364735

potassium是⼀种抗逆转录病毒剂，可抑制⼈类免疫缺陷病毒1型(HIV-1)的整合酶(integrase)，IC50为7.8

nM。

IC50TargetIC50:7.8nM(HIV-1integrase)

REFERENCES

[1].GarveyEP,etal.,ThenaphthyridinoneGSK364735isanovel,potenthumanimmunodeficiencyvirustype1integraseinhibitorand

antiretroviral.AntimicrobAgentsChemother.2008Mar;52(3):901-8.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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