Dihydrocaffeic-acid-Standard-生命科学试剂-MCE.pdf

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Dihydrocaffeicacid(Standard)

Cat.No.:HY-N2406R

CASNo.:1078-61-1

分⼦式:C₉H₁₀O₄

分⼦量:182.17

作⽤靶点:p38MAPK;EndogenousMetabolite;ReactiveOxygen

Species;NOSynthase

作⽤通路:MAPK/ERKPathway;MetabolicEnzyme/Protease;

Immunology/Inflammation;NF-κB

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Dihydrocaffeicacid(Standard)是Dihydrocaffeicacid的分析标准品。本产品⽤于研究及分析应⽤。

Dihydrocaffeicacid是黄酮类化合物的微⽣物代谢产物，可降低MAPKp38的磷酸化⽔平，阻⽌紫外线诱导的

⽪肤损伤。Dihydrocaffeicacid具有抗氧化、抗炎活性[1]。

IC50TargetMAPKp38phosphorylation[1]

REFERENCES

[1].OliveiraMM,etal.DihydrocaffeicAcidPreventsUVB-InducedOxidativeStressLeadingtotheInhibitionofApoptosisandMMP-1

Expressionviap38SignalingPathway.OxidMedCellLongev.2019Jan17;2019:2419096.

[2].BottaG,etal.Carbonnanotubessupportedtyrosinaseinthesynthesisoflipophilichydroxytyrosolanddihydrocaffeoylcatecholswith

antiviralactivityagainstDNAandRNAviruses.BioorgMedChem.2015Sep1;23(17):5345-51.

[3].VázquezR,etal.Structure-anti-leukemicactivityrelationshipstudyofortho-dihydroxycoumarinsinU-937cells:keyroleoftheδ-lactone

ringindeterminingdifferentiation-i