磷酸奥司他韦胶囊联合连花清瘟颗粒治疗流行性感冒的观察.docx

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【摘要】目的：探讨连花清瘟颗粒联合磷酸奥司他韦胶囊对流行性感冒的疗效。方法：选择2023年1月—2023年12月本院门诊收治的流行性感冒患者80例，根据收治顺序并采用随机分组法分为联合组（n=40）和西药组（n=40），联合组口服连花清瘟颗粒和磷酸奥司他韦胶囊，西药组患者口服磷酸奥司他韦胶囊，观察两组中医证候积分变化情况、症状消失时间和治疗总有效率。结果：联合组发热、咳嗽、全身乏力等临床症状消失时间短于西药组，治疗后中医证候总积分低于西药组，差异有意义（P0.05）。联合组治疗总有效率高于西药组，差异有意义（P0.05）。两组不良反应发生率差异无意义（P0.05）。结论：连花清瘟颗粒联合磷酸奥司他韦胶囊对治疗流行性感冒有显著效果，可促进症状改善和疾病恢复，提高治疗总有效率和安全性，可严格掌握剂量、用药时间后进行推广。

【关键词】连花清瘟颗粒；磷酸奥司他韦胶囊；流行性感冒；临床疗效

ObservationofoseltamivirphosphatecapsulecombinedwithLianhuaQingwengranulesinthetreatmentofinfluenza

HUANGJinxia1，2，GEGaiying1，2

1.TheFirstPeople’sHospitalofYinchuanCity，Yinchuan，Ningxia750000，China；2.TheSecondClinicalMedicalCollegeofNingxiaMedicalUniversity，Yinchuan，Ningxia750000，China

【Abstract】Objective：ToinvestigatethetherapeuticeffectofLianhuaQingwengranulecombinedwithoseltamivirphosphatecapsuleoninfluenza.Methods：80patientswithinfluenzaadmittedtotheoutpatientdepartmentofourhospitalfromJanuary2023toDecember2023wereselectedandrandomlydividedintothecombinedgroup（n=40）andthewesternmedicinegroup（n=40）accordingtotheorderofadmission.ThecombinedgrouptookLianhuaQingwengranuleandoseltamivirphosphatecapsuleorally，whilethewesternmedicinegrouptookoseltamivirphosphatecapsuleorally.ThechangeofTCMsyndromeintegral，timeofsymptomdisappearanceandtotaleffectiverateoftreatmentbetweenthetwogroupswereobserved.Results：Thetimeofdisappearanceofclinicalsymptomssuchasfever，coughandgeneralfatigueinthecombinedgroupwasshorterthanthatinthewesternmedicinegroup，andthetotalintegralsofTCMsyndromeaftertreatmentweresignificantlylowerthanthoseinthewesternmedicinegroup（P0.05）.Thetotaleffectiverateofthecombinedgroupwassignificantlyhigherthanthatofthewesternmedicinegroup（P0.05）.Therewasnosignificantdifferenceintheincidenceofadversereaction