Rac-Silodosin-Rac-KAD-3213-生命科学试剂-MCE.pdfVIP

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(Rac)-Silodosin

Cat.No.:HY-10122A

CASNo.:160970-64-9

Synonyms:(Rac)-KAD3213;(Rac)-KMD3213

分⼦式:C₂₅H₃₂F₃N₃O₄

分⼦量:495.53

作⽤靶点:AdrenergicReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(Rac)-Silodosin((Rac)-KAD3213)是Silodosin(HY-10122)的外消旋体。Silodosin是⼀种强效、选择性和具有

⼝服活性的α1A-肾上腺素受体(α1A-AR)阻滞剂。

REFERENCES

[1].ZhaoF,et,al.Design,Synthesis,andBiologicalEvaluationofIndolineandIndoleDerivativesasPotentandSelectiveα1A-

AdrenoceptorAntagonists.JMedChem.2016Apr28;59(8):3826-39.

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