流感、禽流感基本知识与防控PPT课件.ppt

HurwitzE.S.,HaberM.,ChangA.EffectivenessofinfluenzavaccinationofdaycarechildreninreducingInfluenzarelatedmorbidityamonghouseholdcontacts.JAMA,2000-vol284,No13.1.KhanAS.ComparisonofUSinactivatedsplitvirusandRussianliveattenuated,coldadaptedtrivalentinfluenzavaccinesinRussianschoolchildren.JInfectDis,1996.2.WhiteT.,LavoieS.Potentialcostsavingsattributabletoinfluenzavaccinationofschoolagedchildren.Pediatrics,1999ColquhounA.Jetal,Effectivenessofinfluenzavaccineinreducinghospitaladmissionsinpeoplewithdiabetes,Epidemiologyinfectious1997,119:335-341HakEetal.Influenceofhigh-riskmedicalconditionsontheeffectivenessofinfluenzavaccinationamongelderlymembersof3largemanaged-careorganizations.ClinInfectDis2002;35:370-7.*学龄儿童接种疫苗，可降低家庭接触者呼吸道疾病未接种组(n=31)接种组(n=28)日托儿童接种流感疫苗，可使未接种疫苗的家庭接触者发热性呼吸道疾病降低80%，其它呼吸道疾病降低70%以上。发生率HurwitzE.S.,HaberM.,ChangA.EffectivenessofinfluenzavaccinationofdaycarechildreninreducingInfluenzarelatedmorbidityamonghouseholdcontacts.JAMA,2000-vol284,No13.*接种流感疫苗降低学生缺课率流感流行季节每个儿童缺课天数接种疫苗组安慰剂组缺课率降低56%[1]每个儿童节约费用：35美元[2]1.KhanAS.ComparisonofUSinactivatedsplitvirusandRussianliveattenuated,coldadaptedtrivalentinfluenzavaccinesinRussianschoolchildren.JInfectDis,1996.2.WhiteT.,LavoieS.Potentialcostsavingsattributabletoinfluenzavaccinationofschoolagedchildren.Pediatrics,1999*糖尿病患者接种流感疫苗的效益(ColquhounA.Jetal,Effectivenessofinfluenzavaccineinreducinghospitaladmissionsinpeoplewithdiabetes.Epidemiologyinfectious1997,119:335-341英国的病例对照研究显示，接种流感疫苗可使糖尿病患者以下因素导致的住院率降低79%肺炎和流感*支气管炎糖尿病（无并发症）糖尿病昏迷酮症酸中毒*疫苗和循环毒株抗原匹配时*老年人接种流感疫苗的效益老年人接种流感疫苗降低肺炎流感住院风险和全死因死亡风险在1996-97年流感季节高达50%在1997-98年流感季节达21%**1997-98季节疫苗株与循环株匹配较差1996-97和1997-98季节，美国65岁以上糖尿病患者住院率和死亡率HakEetal.Influenceofhigh-riskmedicalconditionsontheeffectivenessofinfluenza