理中汤联合西医治疗对重症颅脑损伤后肺部感染的临床研究.pdfVIP

目录

目录

中文摘要·········································································4

英文摘要·········································································5

英文缩写·········································································6

研究论文

理中汤联合西医治疗重症颅脑损伤后肺部感染的临床研究

前言·······································································7

材料与方法································································9

结果······································································12

附图·······································································14

附表·······································································15

讨论·······································································18

小结·······································································21

结论······································································22

参考文献········································································23

综述重症颅脑损伤后感染及防治的国内外研究现状·············28

致谢···········································································39

个人简历········································································40

-3-

中文摘要

理中汤联合西医治疗重症颅脑损伤后肺部感染的临床研究

摘要

为探索理中汤联合西医治疗应用于重型颅脑损伤（sTBI）后肺部

感染疗效。选择本院80例sTBI患者，随机分为观察组、对照组两组，

每组40例。所有患者在术后开始行重症监护治疗，观察组在常规西

医治疗基础上联合应用理中汤，两组患者均连续治疗10d。治疗结束

后，收集患者治疗前后白细胞计数、降钙素原、超敏c反应蛋白、IgG、

IgM、白蛋白、前白蛋白等实验室指标，比较两组患者治疗前后上述

指标的统计学差异。结果发现治疗10d后观察组的白细胞计数、降钙

素原、白介素6、超敏c反应蛋白、乳酸、中性粒细胞明胶酶相关脂

质运载蛋白(NGAL)、肺部感染持续时间、临床肺部感染评分（CPIS）

明显低于对照组（均P0.05），IgG、IgM、IgA、白蛋白、前白蛋白

等指标改善明显优于对照组（均P0.05）。两组治疗后淋巴细胞亚群

指标差异无统计学意义（均P0.05）。结果提示理中汤可以增强机体

免疫力，降低过度炎症反应，