R-minus-Ibuprofen-Standard-生命科学试剂-MCE.pdfVIP

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(R)-(-)-Ibuprofen(Standard)

Cat.No.:HY-78131BR

CASNo.:51146-57-7

分⼦式:C₁₃H₁₈O₂

分⼦量:206.28

作⽤靶点:NF-κB

作⽤通路:NF-κB

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(R)-(-)-Ibuprofen(Standard)是(R)-(-)-Ibuprofen的分析标准品。本产品⽤于研究及分析应⽤。(R)-(-)-

Ibuprofen是Ibuprofen的R型异构体，对COX⽆作⽤，可以抑制NF-κB的活化；(R)-(-)-Ibuprofen具有抗

炎作⽤，可⽤于缓解疼痛的研究。

IC50TargetNF-κB[2]

REFERENCES

[1].EvansAM,etal.ComparativepharmacologyofS(+)-ibuprofenand(RS)-ibuprofen.ClinRheumatol.2001Nov;20Suppl1:S9-14.

[2].ScheurenN,etal.ModulationoftranscriptionfactorNF-kappaBbyenantiomersofthenonsteroidaldrugibuprofen.BrJPharmacol.

1998Feb;123(4):645-52.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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