抗CD19 CAR-T治疗相关补充数据图表.pdfVIP

抗CD19单链抗体

AVLVHCD8a铰链和TMCD137光盘3ζ

器

B

患者1患者2患者3患者4‑1st患者4‑2nd

s

t

n

u

o

C

CART‑GFP

患者5患者6患者7‑1st患者7‑2nd患者8患者9

s

t

n

u

o

C

CART‑GFP

Anti-CD19scFv

AVLVHCD8ahingeandTMCD137CD3ζ

Linker

B

Patient1Patient2Patient3Patient4-1stPatient4-2nd

13.27%34.74%21.33%19.00%31.05%

s

t

n

u

o

C

CART-GFP

Patient5Patient6Patient7-1stPatient7-2ndPatient8Patient9

44.06%15.47%17.29%25.47%27.36%21.00%

s

t

n

u

o

C

CART-GFP

A

患者1骨髓患者3BM

B

C

患者6脑脊液

A

Patient1BMPatient3BM

B

C

Patient6CSF